Holly tracks an alien-looking ship and Red Dwarf latches onto it with its suction docking clamps. Inside, Kryten and Rimmer find a malformed, triple-headed skeleton and find out that the ship they're in is human in origin. Meanwhile Lister is turned into a chicken by the Cat who tapped keys on a machine in the room they were exploring. Kryten and Rimmer enter the room and realise that the machine is a DNA modifier. After attempting to change Lister back (Kryten turned him into a hamster), the Cat goes over what he did and starts to change Kryten (the machine can work on him because his brain is part organic), he presses some random keys and Lister is changed back to normal, when pressing what he did for Lister to free Kryten, the machine transforms Kryten from a mechanoid into a human.
This has resulted in Kryten's dream of becoming human coming true, physically he has the body of a 30 year old human male, but everything is new to him, after Lister arrived with Kryten's breakfast of "boiled chicken ovulations", he went over a list that Kryten wanted to check, he discovered that human eyes don't have a zoom function, his nipples don't pick up short wave radio transmissions and that he needs to eat and sleep to recharge (not stick a lead in the "socket") and has taken polaroid photos of his penis which he shows to Lister not believing that is how its meant to look. After finding out that super deluxe vacuum cleaners give Kryten a "double Polaroid", Lister tells Kryten he should change back since he was never meant to be human, but Kryten doesn't want to.
Rimmer thinks it's the greatest advancement mankind has ever made and wants to use it to create a new body, cloning it from his old dandruff, but Cat sneezes it away. Cat doesn't want to use it as he doesn't see anything that he wants to improve, Lister believes that Kryten is in for a major disappointment, which he gets when he ends up insulting his Spare Heads (and hand, which gives a two fingered salute in response), this makes Kryten depressed, Lister convinces him to change back by telling of his own shameful instance in which he went against who he really was by going into a wine bar.
When at the DNA suite, Holly gets ready to change Kryten back, but Rimmer wants to test it first using the tin foil container holding Lister's unfinished curry, which results in the creation of the Mutton Vindaloo Beast, a beast that wants them dead and is invulnerable to bazookoid fire, as it is made from vindalooed mutton.
They retreat back to the DNA suite and Lister asks Holly to turn him into "Man Plus", resembling RoboCop, but ended up turning him into a Man Minus, much shorter than intended. When the others run away from the beast, miniature cyborg Lister is cornered and then realises that the beast is burned like acid when it touches Leopard Lager (beer being the only thing that can kill a vindaloo). Lister throws a can of lager into its mouth, and shoots at it with the bazookoid, blowing its head off. When the others return, they are disgusted to find Lister is eating some of the Mutton Vindaloo Beast saying "Has anyone got a poppadom the size of Lake Michigan? This stuff's really good".
As available for viewing on the Series IV DVD:
- At least six cut dialogue scenes and jokes, and with more of the Mutton Vindaloo Beast seen. As it comes at the Robo-Lister, he fires off a number of blasts from the bazookoid which miss the Leopard Lager can in the beast's maw, before finally hitting it and blowing up the beast (therefore more closely mimicking the ending of Jaws).
- It is noted by Lister that the events of this episode take place exactly "one year to the day" from the events in the episode "Polymorph", on Easter.
- This episode marks the first appearance of Kryten's Spare Heads, and notably Spare Head 3.
- Lister mentions Kryten (after he insulted his spare heads) having his "head up his recharge socket", which hints at where it is located.
- The hologram Rimmer finds a three-million-year-old piece of his dandruff, the only thing left of his former human self. Rimmer intends to use the DNA Ship to recreate his physical body from the genetic structure within the dandruff; however the Cat scuppers this plan by sneezing the speck away. This concept is reused from the "lost episode" of Series I, "Bodysnatcher", where a similar event occurs.
- The D.N.A. Machine recognizes Lister's accent as a "colloquial English Dialect, 23rd Century". This is strange given that other episodes have said Lister comes another century, such as the 21st century (for example in "Stasis Leak"), and also from the 22nd century (such as in "Ouroboros"). This inconsistency has never fully been resolved, although multiple time-lines have been created and ended throughout the run of the show ("Timeslides", "White Hole", "The Inquisitor", "Out of Time", "Pete"), which may go some way to explaining it.
- On the DNA ship, the boys find a mutated astro with three heads. In the Series VIII episode "Krytie TV", the encounter a similar mutant.
- Kryten: ...Oh. Wait a minute. No. My brain is part-organic, and therefore it is entirely possible for the machine to transmogrify my physical condition. Engaging panic circuits. Panic circuits engaged. Mwah-heh! (Cries)
- Human Kryten: (Hands Lister a photo. After realising what it is of, Lister turns away) Well?
Lister: We-we-well what?
Human Kryten: Well, what do you think?
Lister: I'm not quite with you here, Kryten. What am I supposed to say?
Human Kryten: Well, I want to know is that normal?
Lister: What? Taking photographs of it and showing it to your mates? No, it's not!
- The Cat: Last time, it was hors d'oeurves... this time, it's lunch!
- Kryten: You sold out? Hmm.
Lister: Look, this is between me and you, OK, Kryten? Once, many years ago I went into a wine bar.
Kryten: That's it? You went into a wine bar? - OK.
Lister: Keep it down! - I don't want the whole world to know.
Kryten: What's so bad about going into a - a "WB"?
Lister: It means I was a class traitor. I could have been on that slippery slope - hankering after pine kitchens, sleeping on futons, eating tapas. Who knows? I could have started having "relationships" instead of "going out", got married, got on the property ladder. Who knows where it could have ended? Next thing you know, I'm playing squash every Tuesday night with a bloke called Gerald. A lucky escape, man.
Kryten: I want to be a mechanoid again.
- The name of the episode 'D.N.A.' is described in the commentary on the DVD as standing for 'Do Not Alter'. Although, it is noteworthy that the acronym D.N.A. also stands for Deoxyribonucleic Acid, the basic building blocks of life.
- This episode has several (subtle) references to Hitchhikers Guide to the Galaxy. D.N.A are the initials of Douglas Noel Adams. It is episode 2 of series 4, which could be written as episode 4.2 - leave out the dot and you get 42. The skeleton with additional heads could be be a reference to Zaphod Beeblebrox.
- Lister's reaction to Kryten's "double Polaroid" was not actually planned: Craig Charles had no idea he'd be seeing the real thing, and was quite startled when he realized what it was.
- This is one of two episodes in Series IV that allowed Robert Llewellyn to perform scenes outside of his cumbersome Kryten makeup.
- A scene was filmed with the three-headed mutant corpse falling through Rimmer, but this was cut it only talked about.
- Lister's relationship with Kochanski is retconned in this episode; while he was established to have merely pined after her before, it is now stated that (just like in the novel) the two did enjoy a brief relationship.
Actor and character they played.
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